We’ve determined that high blood sugar downregulates the main signal transduction component employed by the IGF-I receptor: IRS-1 [14]. SHPS-1…

(a) Effect of forced expression ((shRNAi1) on cell growth was measured at 12?h intervals. cellular proliferation, invasion, and tumorigenic activity…

Person Dll1 or Dll4 neutralization via peri-transplant antibody-mediated blockade induced protecting effects indistinguishable from those seen with hereditary pan-Notch inhibition…