Small molecule KDM4s inhibitors As Anti-Cancer Chemotherapeutics

KDM4s inhibitor

Category: p75

p75

?Fig

Nov 4, 2022 admin

?Fig.6,6, both tests revealed that treating cells with 10 M of MI-319 every day and night induced significant apoptotic cell…

p75

In principle, better strength and efficiency of the nilotinib analogue that presents zero or minimal connections with P-gp and ABCG2 but nonetheless inhibits the kinase (although with lower performance) might outweigh the advantage of using the parent nilotinib drug, which inhibits the kinase but also interacts efficiently with ABCG2 and P-gp

Dec 30, 2021 admin

In principle, better strength and efficiency of the nilotinib analogue that presents zero or minimal connections with P-gp and ABCG2…

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