Consequently, proteomics analysis-the direct evaluation of the expression levels and modifications of proteins-has been focused on recently as a powerful exploration method for identifying predictive biomarkers for the efficacy of chemotherapeutic medicines
Consequently, proteomics analysis-the direct evaluation of the expression levels and modifications of proteins-has been focused on recently as a powerful…
2009;20:671C679
2009;20:671C679. (RR 0.93, 95 % CI 0.88-0.97) and good sized test size (RR 0.94, 95 % CI 0.91-0.98). There is…
Among the most challenging aspects of adoptive cell therapies and CAR-T engineering are the identification and use of antigens for focused immune effector cell activation to cancer targets only
Among the most challenging aspects of adoptive cell therapies and CAR-T engineering are the identification and use of antigens for…
In the phase III ULTIMATE trial,19 166 patients with advanced NSCLCs progressing after first- or second-line therapy were randomized to receive weekly the paclitaxelCBVZ combination compared to docetaxel; progression-free survival (PFS) was significantly longer for the former group but overall survival (OS) was comparable for the two groups
In the phase III ULTIMATE trial,19 166 patients with advanced NSCLCs progressing after first- or second-line therapy were randomized to…
More research is necessary for selective inhibitors that could help understand not merely the function of different ceramidases, but also their development into more promising and efficacious therapeutics to regulate ceramide-related pathologies
More research is necessary for selective inhibitors that could help understand not merely the function of different ceramidases, but also…
Five weeks following AOM treatment, rats were fed with experimental diet programs containing aspirin at 700 and 1,400 ppm and naproxen at 200 and 400 ppm (continuously or intermittent dosing: seven days on/1 week away; or three weeks on/ three weeks off) and an individual dosage of 2,800 ppm aspirin intermittent dosing (three weeks on/ three weeks off)
Five weeks following AOM treatment, rats were fed with experimental diet programs containing aspirin at 700 and 1,400 ppm and…
A non-paired Student’s test)
A non-paired Student’s test). Table 1 Comparison of Cannabinoid type-1 Receptor affinity with potency and efficacy for Adenylyl Cyclase Inhibition…
Importantly, the three pyrazolotriazinones assayed were able to increase the cell viability measured by the MTT test to the same level than the standard TDZD-8 does, probably due to the decrease on tau phosphorylation by GSK-3 inhibition
Importantly, the three pyrazolotriazinones assayed were able to increase the cell viability measured by the MTT test to the same…
Furthermore, incubation of ovarian fragments using a focus of gonadotropin that promotes oocyte maturation causes receptor concentrations to improve several-fold to attain peak levels at the start of oocyte maturation [50]
Furthermore, incubation of ovarian fragments using a focus of gonadotropin that promotes oocyte maturation causes receptor concentrations to improve several-fold…
These effects seem in charge of the decreasing of sugar levels in vivo, via glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase [58]
These effects seem in charge of the decreasing of sugar levels in vivo, via glucose utilization and fatty-acid oxidation by…