In the phase III ULTIMATE trial,19 166 patients with advanced NSCLCs progressing after first- or second-line therapy were randomized to receive weekly the paclitaxelCBVZ combination compared to docetaxel; progression-free survival (PFS) was significantly longer for the former group but overall survival (OS) was comparable for the two groups

In the phase III ULTIMATE trial,19 166 patients with advanced NSCLCs progressing after first- or second-line therapy were randomized to…

Five weeks following AOM treatment, rats were fed with experimental diet programs containing aspirin at 700 and 1,400 ppm and naproxen at 200 and 400 ppm (continuously or intermittent dosing: seven days on/1 week away; or three weeks on/ three weeks off) and an individual dosage of 2,800 ppm aspirin intermittent dosing (three weeks on/ three weeks off)

Five weeks following AOM treatment, rats were fed with experimental diet programs containing aspirin at 700 and 1,400 ppm and…