Small molecule KDM4s inhibitors As Anti-Cancer Chemotherapeutics

KDM4s inhibitor

Month: March 2025

P-Type ATPase

(a) Illustration of PD-L1 bioassay: Anti-PD-L1 arm of anti-PD-L1/CD40L BsAbFP inhibits the PD-1/PD-L1 pathway leading to the activation of luciferase reporter gene in Jurkat/PD-1/NFAT-Luc cell; (b) Illustration of CD40L bioassay: CD40L arm of anti-PD-L1/CD40L BsAbFP binds to CD40 leading to the activation of luciferase reporter gene in Raji/NFB-Luc cell; (c) Representative PD-L1 bioassay graph comparing dose-dependent response between of anti-PD-L1/CD40L BsAbFP and anti-PD-L1 mAb; (d) Representative CD40L bioassay graph comparing dose-dependent response between anti-PD-L1/CD40L BsAbFP and CD40L

Mar 2, 2025 admin

(a) Illustration of PD-L1 bioassay: Anti-PD-L1 arm of anti-PD-L1/CD40L BsAbFP inhibits the PD-1/PD-L1 pathway leading to the activation of luciferase…

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